Searchable abstracts of presentations at key conferences in endocrinology

ea0032p757 | Obesity | ECE2013

Adiponectin and leptin actions on DNA synthesis and cell death of porcine myoblasts are dependent on the cellular milieu and related to ERK1/2 signalling

Kuzinski Judith , Will Katja , Kalbe Claudia , Maak Steffen , Palin Marie-France , Rehfeldt Charlotte

Cross-talk between adipose tissue and skeletal muscle could be mediated in part by adipokines secreted from adipose tissue. Previously, we observed that adiponectin but not leptin decreased DNA synthesis rate in proliferating porcine myoblasts in growth factor-supplemented serum-free medium (GF-SFM) after 48-h exposure (Will et al. 2012). To further elucidate the effects of adiponectin and leptin on muscle cell growth and their mode of action, this study was conducted...